Discoveries, patents, publications, treatment

Research Results

Focusing on detail

Research Results

Searching for new and more effective ways of treatment

Research Results

Modern equipment, top-class physicians and researchers
= satisfied patients

Research Results

Introduction

FNUSA-ICRC is a multidisciplinary center
of excellence in translational medical research.

FNUSA-ICRC location, Brno, Czech Republic

FNUSA-ICRC building, Brno, Czech Republic

The International Clinical Research Center (FNUSA-ICRC) established in 2011 is an integral part of St. Anne’s University Hospital in Brno (FNUSA), one of the traditional university hospitals in the Czech Republic and a former workplace of Johann Gregor Mendel. Despite being established only in 2011, FNUSA-ICRC has already become a center of excellence in many fields of clinical, translational, and basic research and currently takes pride in employing over 200 people from 16 countries with 35 % of foreign researchers.

24 research teams and 5 core facilities follow the mission of FNUSA-ICRC and create the future of medicine by finding new solutions for prevention, diagnostics and treatment of cardiovascular, neurological and selected oncological diseases and disorders.

FNUSA-ICRC aims to improve health care and the quality of life through linking clinical care, research and development, education and cooperation with the industrial sector.

FNUSA-ICRC PROFILE SHEET

Our Mission, Visions and Goals

FNUSA-ICRC has been built to integrate international multidisciplinary research with education and training through intensive international exchange of ideas and personnel -  with close transfer of knowledge between academia and industry, for the benefit of patients of St. Anne´s University Hospital and worldwide who thanks to the activities of our center have access to latest discoveries in medical research, novel pharmaceuticals and medical devices not yet available on the market, as well as novel diagnostic and therapeutic methods.

Vision of FNUSA-ICRC: FNUSA-ICRC powers innovations in healthcare by its discoveries in understanding development and progression of human diseases.

Mission of FNUSA-ICRC: Inspired by the patients, FNUSA-ICRC researchers create the future of medicine by translating clinical findings into discoveries and vice versa.

GOALS

  • Excellence in translational research
  • Promotion of healthy aging
  • Intimate partnership with industry
  • Giving back to the commmunity

Corporate motto of FNUSA-ICRC:

"Creating the future of medicine"

ICRC Research Vision and Misison

4 Areas of Our Activities:

FNUSA-ICRC has been built to integrate international multidisciplinary research with education and training through intensive international exchange of ideas and personnel, and with close transfer of knowledge between academia and industry, for the benefit of patients of St. Anne´s University Hospital and worldwide who thanks to the activities of our center have access to latest discoveries in medical research, novel pharmaceuticals and medical devices not yet available on the market, as well as novel diagnostic and therapeutic methods.

An international research and development center

A public health care center

An international education center

A center for cooperation with industry

History of FNUSA-ICRC

FNUSA-ICRC Milestones

Period of sustainability.

FNUSA-ICRC Management

Gorazd B. Stokin, M.D., MSc., Ph.D.

Gorazd B. Stokin, MD, MSc., Ph.D.

FNUSA-ICRC Chair

Gorazd Bernard Stokin graduated from the School of Medicine of the University of Trieste, Italy, received doctorate in Neuroscience from the University of California San Diego, USA, and trained in neurology at the University of California San Diego, USA, University of Cambridge, UK, and the University Medical Centre Ljubljana, Slovenia. He is specialised in behavioural and cognitive neurology, while his research focuses on early events that underlie development of Alzheimer’s disease. His work uncovered the intimate relationship between impairments in axonal transport and Alzheimer’s diseases and more recently with traumatic brain injury. Dr. Stokin serves on several committees, boards and panels involved in dementia care and research. In 2016 he was elected Fellow of the American Academy of Neurology. Dr. Stokin has been chairing FNUSA-ICRC since May 2013 where he also developed Translational Neuroscience and Ageing Program, a Laboratory aiming to understand the very mechanisms underlying development of Alzheimer’s disease.

Pavla Seilerová, MA

Pavla Seilerova, MA

Chief Financial Officer

Pavla Seilerová has been working at the International Center for Clinical Research at St. Anne's University Hospital in Brno since 2012, at the position of Financial Director since 2015. She has ten years of experience in corporate banking. She graduated from the Faculty of Economics and Business of the Mendel University in Brno. During her work at FNUSA-ICRC she has completed several professional courses focused on science and research funding both in the Czech Republic and abroad. In July 2018, she began her Ph.D. studies at Tomas Bata University in Zlín, specializing in the financial field. That represents a great opportunity to connect practical experiences with theory. In her research she focuses on research infrastructures funding with the aim to create a complex Core-Facilities Funding Model.

René Samek, MSc., MA

Rene Samek, MSc., MA

Director for External Affairs

René Samek did his graduate studies at Charles University in Prague, Central European University in Budapest and London School of Economics. He worked for 10 years for the national investment promotion and business development agency CzechInvest, as the Marketing & PR Manager, Head of the UK & Ireland office, and Director of Investment and Applied Research Support Division. Then he worked for at AIG/Lincoln, the U.S. company which develops industrial zones and office parks in Central and Eastern Europe. In 2010-2012 he participated in the national project of the Czech Ministry of Education, Youth and Sports which developed a methodology for technology transfer for Czech research institutions. He also worked as a consultant in more than 10 economic development projects financed by the European Union, Czech Ministry of Foreign Affairs, United Nations Development Program and Columbia University, which were implemented in Eastern Europe, Asia and Africa.

Dr. Alena Kružíková

Dr. Alena Kruzikova

Head of the Human Resources Department

Alena Kružíková graduated from the Faculty of Science specializing in mathematics and geography. She has experience in the complete management of personnel processes in international manufacturing companies. In her previous jobs, she has been involved in implementation of educational projects, introduction of career programs, cooperation with academia, employing foreigners. She also has experience with successful implementation of human resources information systems, introducing employee evaluation and remuneration systems, competence models. HR work for her is, according to her own words, a life-long mission and a hobby, and work for FNUSA-ICRC specifically at the position of Head of the Human Resources Department, an honor. She very much appreciates the enthusiasm and devotion to science and research of all members of the great international FNUSA-ICRC team.

Michal Janota, MA

Michal Janota, MA

Chief Operation Officer

Michal Janota is the Chief Operation Officer of the International Clinical Research Center of the Saint Anne´s University Hospital in Brno. He graduated from the Faculty of Science, Masaryk University, Brno, the Czech Republic. During his studies he was working for the Regional Development Research Center by Masaryk University where he led the administration office and was responsible for managing grants/commercial projects and everyday operations. He contributed to labor market and economic analyses for South Moravian region and led a project of creating a strategic-planning documentation for chosen municipalities districts. Before he joined FNUSA-ICRC in 2011 he worked in private sector as a Project manager of financial subsidies for small and medium enterprises focused mainly on technologies investments and HW/SW solutions development. Since 2014 he is leading strategic projects of developing specific Research Information system for FNUSA-ICRC involving also solution for the infrastructure and Core-Facility management.

FNUSA-ICRC Supervisory Board Members (FNUSA-ICRC SB)

The Supervisory Board is the highest supervisory body of FNUSA-ICRC. It supervises all FNUSA-ICRC activities particularly in the fields of research and development, technology transfer, education, human resources, economy, and legal and ethical issues.

Martin Pavlík

Martin Pavlik, MD, Ph.D., DESA, EDIC

Dr. Martin Pavlik is the director of St. Anne’s University Hospital Brno (FNUSA), and also works as a doctor and university lecturer. Since 2006 he has been deputy chief for therapeutic and preventive care at the FNUSA Anesthesiology and Resuscitation Clinic. He also worked abroad: York, England; Austria; and Sydney, Australia. He is behind the Medical Emergency Team System project implementation. He also acts as a member of the Professional Board of the Ministry of Health and Scientific Board of the Medical Faculty at Masaryk University in Brno.

Jan Zaloudik

Prof. Jan Zaloudik

Prof. Jan Zaloudík is a Czech politician and physician. Between 1979 and 2010, he worked at the Masaryk Memorial Cancer Institute (MMCI) in Brno as a surgeon and oncologist, and eventually became the MMCI’s Director (2000-2001). He returned to this position 13 years later and has held it ever since. Between 1999 and 2002, he was the Vice-Dean for Science and Research at the Faculty of Medicine, Masaryk University; between 2003 and 2010, he was the Dean of the Faculty. Prof. Zaloudik also has professional experience abroad. He worked as a researcher at the Paterson Institute for Cancer Research and Christie Hospital (UK), the Wistar Institute and also at The University of Pennsylvania (USA).

Thomas Braun

Prof. Dr. Habil. Thomas Braun

Prof. Dr. Habil. Thomas Braun, Director and Scientific Member at the Max Planck Institute for Heart and Lung Research He studied philosophy and medicine in Göttingen and Hamburg, PhD in Medicine (1987), German Habilitation in biochemistry (1993), University of Hamburg, Professor at the University Halle-Wittenberg, Director of the Institute of Physiological Chemistry (1998-2004).

Jan Stransky

Martin Jan Stransky, MD, FACP

Martin J Stránský MD FACP is a neurologist, founder and Director of the Policlinic at Národní in Prague, Assistant Clinical Professor in Neurology at Yale, founder of the Office of the Ombudsman of the Czech Republic, and Publisher of the magazines Přitomnost and The New Presence. He lectures at the international level on the negative effects of modern technology on the human brain, is an advisor on healthcare systems to numerous government officials and international organizations and is an organizer of international programs in medical education.

Jakub Tolar

Jakub Tolar, MD, Ph.D.

Jakub Tolar is a dean of the University of Minnesota Medical School and a Professor in the Department of Pediatrics, Blood and Marrow Transplantation. Jakub Tolar received his medical education in Prague at the Charles University. In 1992, he came to the University of Minnesota, where he completed his Ph.D. in Molecular, Cellular & Developmental Biology and Genetics. Since 2011, Jakub Tolar is a director of the Stem Cell Institute of the University of Minnesota.

Pavel Trcka

Pavel Trcka, M. Sc.

Pavel Trcka is an independent consultant in corporate finance. He graduated from the School of Economics, Bratislava, in International trade and International finance. His banking career started in 1990 in Citibank a.s. Prague in the position of head of the consulting department for international investors in Czechoslovakia, later as a senior relationship manager for international companies. Between 1993 and 2009 he worked in Raiffeisenbank a.s. specializing in the financing of companies and foreign trade.

Robert G. Will

Robert G. Will, CBE, MA (CANTAB), MD, MB, BCHIR, FRCP, FMEDSCA

Robert G. Will CBE MA (Cantab) MD MB BChir FRCP FMedSci is a Professor of Clinical Neurology at University of Edinburgh and member of its Centre for Clinical Brian Sciences, multidisciplinary translational centre combining basic and applied research to study the causes, consequences and treatment of major brain disorders.

Miroslav Zámečník

Miroslav Zamecnik

Miroslav Zamecnik is a Czech economist and publicist specializing in financing and economics of healthcare systems. He graduated from the University of Economics in Prague and participated in the Pew Fellow Program of Georgetown University (Washington, D.C.). In the early 1990s he was the Director of Center for Economic Analyses in the office of President Vaclav Havel. During 1994-1998 he was the Czech representative at the World Bank, in 1998-1999 he worked at Arthur D. Little as a Senior Consultant for the Czech Ministry of Finance. During 2000-2001 he worked as the Deputy-Director of the government company restructuring body Revitalisation Agency and the Deputy-Director of the government-owned Consolidation Bank.

Robert Zorec

Prof. Robert Zorec, B.Sc., M.Sc., Ph.D.

Robert Zorec is Professor of Pathophysiology at the University of Ljubljana, Medical Faculty. He is a Member of Slovenian Academy of Sciences and Arts and Academia Europaea. Dr. Zorec received his Ph.D. from the University of Ljubljana in 1986 for his work conducted at the Newcastle Medical School. Dr. Zorec postdoctoral experience was at Cambridge in Dr. W. T. Mason´s laboratory. Since 1991 he has been the Head of Laboratory of Neuroendocrinology-Molecular Cell Physiology. In 1997 he received the Republic of Slovenia Prize for Science. In 2000 he established the Cell Engineering Laboratory BIOMEDICAL, Ljubljana where he has been a CEO since 2006.

FNUSA-ICRC International Scientific Advisory Board Members (FNUSA-ICRC ISAB)

ISAB advises and recommends the Chair of ICRC the strategies for research and evaluates activities and results of FNUSA-ICRC research teams.

Prof. Dr. Ales Blinc, Dr. Med.

Ales Blinc received his MD and DSc degrees from the Faculty of Medicine, University of Ljubljana, Slovenia. From 1991–93 he was a visiting research fellow at the Department of Medicine, University of Rochester, New York. In Slovenia, Dr. Blinc is certified in internal medicine and cardiology – vascular medicine. His research interests range from mechanisms of thrombosis to epidemiology of atherosclerotic vascular disease. Since 2010, Dr. Blinc is Head of the Department of Vascular Medicine, University of Ljubljana Medical Centre, and Professor of Medicine at Faculty of Medicine, University of Ljubljana.

Prof. John Cleland

Professor Cleland qualified in medicine at the University of Glasgow, Scotland in 1977. After a period of postgraduate training and research he was appointed as Senior Lecturer in Cardiology and Honorary Consultant Cardiologist at St Mary’s Hospital, Paddington and the Hammersmith Hospital, London from 1986-1994. In 1994 he was awarded a Senior Research Fellowship by the British Heart Foundation for clinical research in the area of heart failure. In 1999 he was appointed to the Foundation Chair of Cardiology at the University of Hull.

Hana Dawson, MD, Ph.D.

Dr. Dawson received her MD degree from 1st Medical School of Charles University in Prague and her PhD degree from University of South Florida in 1996. She is currently an Assitant Professor of Neurology at Department of Neurology, Duke University School of Medicine and Duke University Medical Center.

Sreeganga S. Chandra, Ph.D.

Sreeganga S. Chandra received her BSc degree from St. Joseph's College, Bangalore, India, in 1989 and Ph.D. in Chemistry from Purdue University in the USA in 1997. In her postdoctoral research, she pursued her interest in neuronal cell biology and neurodegeneration in the lab of Thomas C. Südhof at UT Southwestern Medical Center at Dallas. She is currently an Associate Professor of Neurology and Assistant Professor of Molecular, Cellular, and Developmental Biology in the Department of Neurology, Yale University Medical School and in the Yale Program in Cellular Neuroscience, Neurodegeneration and Repair.

David A. Kass, MD

David A. Kass, M. D. received his B. A. in applied physics & engineering from Harvard University in 1975 and earned his M. D. from Yale University School of Medicine in 1980. He completed his residency at George Washington University School of Medicine in internal medicine, followed by a cardiology fellowship at Johns Hopkins University School of Medicine. He is currently the Director at the Johns Hopkins Center for Molecular Cardiobiology and a Professor in Cellular and Molecular Medicine at Johns Hopkins University School of Medicine.

Brett Kissela, MD, MS

Brett Kissela, MD, MS is Professor and Chair of the Department of Neurology and Rehabilitation Medicine and Senior Associate Dean for Clinical Research at the University of Cincinnati College of Medicine, and Chief of Research Services for UC Health. He is fellowship trained in Vascular Neurology and has extensive clinical trial experience in acute stroke treatment, prevention, and recovery trials. He is an internationally recognized expert on causes, outcomes, and recovery of stroke, with a special interest in the impact of diabetes on stroke and factors that influence stroke outcomes. Honors and awards include the Michael S. Pessin Stroke Leadership Prize from the American Academy of Neurology.

Kenneth Moya, Ph.D.

Dr. Moya studied biology and medicine at Harvard University and received his PhD degree from Massachusets Institute of Technology in 1989. He has taught at the Center for Interdisciplinary Research in Biology and the École normale supérieure in Paris, France.

Prof. Peter Nestor, MD

Peter Nestor studied medicine at the University of Melbourne, Australia, graduating in 1989. He moved to the University of Cambridge in 1998 where he completed a PhD on positron emission tomography in dementia and then remained on in Cambridge as a research associate. He became a Medical Research Council clinician scientist in 2005 and a senior research associate at the University of Cambridge. From 2009 he was university lecturer in cognitive neurology also at the University of Cambridge. In 2012 he moved to the German Center for Neurodegenerative Diseases where he is a group leader focusing on Alezeimer´s Disease.

Jana Lizrova Preiningerova, MD

Dr. Preiningerova trained at 1st Medical School of Charles University in Prague and also trained at Yale University. In 2004-2010 she was an Assistant Professor in Neurology at Yale University School of Medicine, Director of the Neuro-imunology Program at Yale University New Haven Hospital and directed the Yale Multiple Sclerosis Center (CT, USA) where she developed a comprehensive care program and clinical research team. Since 2009 she is a Professor of Medicine at Charles University in Prague (1st Medical School ) and neurologist at Neurology Department at the General University Hospital in Prague, specialising in multiple sclerosis.

Marcelo Rubinstein, MD

Dr. Rubinstein studied medicine and mollecular biology in Argentina and the United States. He was an International Scholar and Research Fellow with the Howard Hughes Medical Institute in the USA 1997-2011. He is a Laboratory Director at the National Scientific and Technical Research Council of Argentina, Principal Investigator at and Associate Profesor at Faculty of Exact and Natural Sciences of the Universidad de Buenos Aires.

Gustavo Sevlever, MD

Dr. Sevlever received hos MD degree from the Medical School of University of Buenos Aires and also studied at University of California San Diego. He is the Chair of the Neuropathology and Molecular Biology at FLENI neurological institute in Buenos Aires and is one of the leading experts on the use of stem cells in neurology. 

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