The plasticity of cancer cells is one of the factors that significantly contributes to the progression of cancer, as well as its response and resistance to the therapy being applied. The ability of some cancer cells to change their transcriptional activity and avoid the effects of therapy is surprising and still relatively unexplored.

The main objective of the research team is to understand the plasticity and heterogeneity of tumour cells and the role of the tumour environment in regulating the development of cancer. Cell plasticity is considered one of the main factors contributing to resistance to chemotherapy and to bad prognoses. The team is analysing the phenotypic characteristics of cells in order to understand the molecular mechanism associated with cell plasticity and its role in the development of cancer.

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