Every year, circulatory system diseases are the cause of death for more than one-half of those who die, with the largest portion being represented by ischemic heart disease (IHD). Ischemic heart disease has long been one of the most commonly occurring diseases in the Czech Republic, with around 22,000 people being hospitalized with its acute form, myocardial infarction, every year. In the Czech Republic, approximately 51,000 people die because of heart and blood vessel diseases, and heart attack is the most common cause.

The research team is primarily focused on acute forms of CAD, such as acute myocardial infarction and unstable angina pectoris, and is helping to pioneer the most effective method for their treatment, called percutaneous coronary intervention (PCI). The research also deals with developing new imaging methods and developing PCI techniques and materials, especially intracoronary stents, which are used in PCI. It is also aimed on methods of treatment for patients with acute myocardial infarction with ST elevations and diseases of multiple arteries and on anti-aggregation treatment or takotsubo cardiomyopathy, a rare condition sometimes knows as the broken heart syndrome.

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