Every year, almost 15 million people around the world get cancer, and almost 9 million die from the disease. In the Czech Republic, cancer is diagnosed in more than one-fifth of all deceased, which makes it the second most common cause of death in the country. Currently, around 300,000 patients suffer from some form of cancer, and approximately 95,000 people are diagnosed with the disease every year, 350–400 of which are children. Around the world, approximately 300,000 children are diagnosed with cancer every year, and 80,000 children die from it.

The objective of the laboratory translational research, which focuses primarily on paediatric oncology, is to bring new insights from tumour biology into practice. In order for the research conducted in laboratories to be applied to create new methods for treating patients as soon as possible, the team is working closely with clinical oncologists and pathologists. The team is focusing on making a detailed molecular characterization of specific tumours, a description and verification of candidate tumour markers and studying mechanisms of combined antitumor therapies.

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