19. 2. 2021 |

St. Anne's University Hospital Brno (FNUSA) received almost CZK 48 million from a public tender from the Ministry of Health of the Czech Republic to support applied medical research. Of the record number of fifty projects prepared, eleven succeeded. "In a extremely busy competition, success of over twenty percent is a great result. It is proof of the excellent work of all researchers, "said Pavel Iványi, MBA, LL.M., Executive Director of the International Clinical Research Center of St. Anne's University Hospital Brno (FNUSA-ICRC).
 
Among the supported projects, where the main researcher is from FNUSA, the FNUSA-ICRC Stroke Research Team achieved an exceptional result. Two of his projects will be financed - A comprehensive integrated framework of health care to improve the outcome of patients after a stroke in the Czech Republic (CARES CZ) with the main researcher prof. MUDr. Robert Mikulík, Ph.D. and Biocompatible nanoparticles as targeted drug delivery systems and theranostics for the treatment of stroke submitted by doc. RNDr. Jaroslav Turánek, CSc. Another selected project will focus on the training of respiratory muscles as a method of pre-habilitation before pulmonary resection, the main researcher is doc. MUDr. Ivan Čundrle, Ph.D. from the Anesthesiology and Resuscitation Clinic of FNUSA. Of the eleven successful projects, one was also junior (the age of the researcher is up to 35 years), namely Memory of innate immunity as a tool for the body's defense against microbial and SARS-CoV-2 pneumonia with a severe course. Main researcher is Marco De Zuani Ph.D. from the FNUSA-ICRC Cellular and Molecular Immunoregulation Research Team.

Approved projects where FNUSA is a partner will focus on, for example, research into Parkinson's disease, epilepsy or Alzheimer's disease. It is also worth mentioning that the project Use of high-frequency ECG to predict negative remodeling of the left ventricle during chronic pacing stimulated, in which Ing. Pavel Leinveber from the FNUSA-ICRC Biomedical Engineering research team will participate was the best in the Circulatory system diseases section.

"It is a respectable performance if we realize that the projects were prepared by doctors and researchers with a high workload, moreover, in such a difficult situation due to the COVID-19 pandemic," emphasized doc. MUDr. Jan Krejčí, Ph.D., FNUSA Deputy for Science and Research.

Congratulations to all successful solvers and we look forward to the results of the research!

Complete list of successful projects:
Solution projects:
NU21-09-00548 A comprehensive integrated framework of health care to improve the outcome of patients after a stroke in the Czech Republic (CARES CZ) prof. MUDr. Robert Mikulík, Ph.D.
NU21-06-00086 Respiratory muscle training as a way of pre-habilitation before pulmonary resection doc. MUDr. Ivan Čundrle, Ph.D.
NU21-08-00510 Biocompatible nanoparticles as targeted drug delivery and theranostics systems for the treatment of stroke doc. RNDr. Jaroslav Turanek, CSc.
NU21J-05-00056 Memory of innate immunity as a tool for the defense of the organism against microbial and SARS-CoV-2 pneumonia with severe course Marco De Zuani, Ph.D.
Co-research projects:
NU21-04-00445 Clinical response to STN-DBS in Parkinson's disease: influence of vascular, cardiovascular, metabolic and inflammatory comorbidities prof. MUDr. Ivan Rektor, CSc.
NU21-04-00254 Detection of seizure onset zone in multi-lesional epilepsy using multimodal neuroimaging prof. MUDr. Milan Brázdil, Ph.D.
NU21-04-00305 Analysis of transcriptome and DNA methylation in patients with focal cortical dysplasia MUDr. Martin Pail, Ph.D.
NU21-05-00438 The role of alternative forms of uPAR in the development of immunopathological reactions - MUDr. Roman Hakl
NU21-08-00373 Pathogen-induced senescence as a triggering factor of Alzheimer's disease - MUDr. Kateřina Sheardová
NU21-06-00408 Predictive potential of dynamic changes in neutrophil and monocyte subpopulations in the development of SIRS and sepsis after surgery or trauma. - Mgr. Jan Frič, Ph.D.
NU21-02-00584 Use of high-frequency ECG to predict negative left ventricular remodeling in chronic pacing - Ing. Pavel Leinveber


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