Angewandte Chemie Logo

20. 2. 2019

The head of our Medicinal Chemistry research team, Assoc. Prof. Kamil Paruch and other scientists from a broader group of biomolecular and cellular engineering contributed to an article published by Angewandte Chemie with an impact factor of 12.102.
The article titled Furo[3,2-b]pyridine: A Privileged Scaffold for Highly Selective Kinase Inhibitors and Effective Modulators of the Hedgehog Pathway is a result of an equal collaboration with two leading scientists of chemical biology field, Stefan Knapp from University of Oxford and Herbert Waldmann from Max Planck Institute of Molecular Physiology.

PNAS Journal Logo

15. 2. 2019

Bioinformatics and experimental biologists from Loschmidt Laboratories and the FNUSA-ICRC Protein Engineering research team, led by Prof. Jiří Damborský and Prof. Zbyněk Prokop, worked together with a Nobel Prize laureate in Chemistry Arieh Warshel, who received the award in 2013 for the development of computer models of complex chemical systems.
Scientists have engaged in enzymatic reactions to improve their properties for practical use. Nobelist Warshel and his team dealt with theoretical calculations of enzyme variants, our scientists in Brno then experimentally created and tested the variants. Laboratory experiments were carried out by a student of molecular biology Kateřina Slánská, who was interested in the research project within the ICRC Academy. Research has shown that the chosen computational methods have great potential for the formation of new enzyme variants, which could then be used, for example, in the manufacture of drugs or the disposal of toxic substances. In January, the results of a joint scientific study published the Proceedings of the National Academy of Sciences of the United States of America (PNAS) journal.

Visit Brno region official logo
FNUSA-ICRC Talents wanted
Brno region official logo

4. 2. 2019

Information about our center is now available at The website introduces the city of Brno and the life in it to foreigners. It attracts them to study in Brno or to work in one of its companies or institutions.

Besides the brief introduction of the center, you can also read a short commentary from one of our researchers.
Ana Rubina Perestrelo
is a Portuguese native from Madeira island and she moved to Brno 2014 and has stayed in the city thanks to its friendly atmosphere ever since.
Feel free to read more

Did you know?

Our center already employs foreigner workers from 20 countries - from India, Italy, Canada, Portugal, Spain, the United Kingdom and other parts of the world. For example, there are 18 Italians who work in the center and a year ago, even a baby was born to one of our Italian couples in Brno. Foreigners make up more than 20% of the center's employees and we are open to other talented colleagues from abroad.

Dr. Sabine Ernst from Faculty of Medicine and National Heart & Lung Institute of Imperial College London

21. 1. 2019

FNUSA-ICRC was privileged to host Dr. Sabine Ernst from Faculty of Medicine and National Heart & Lung Institute of Imperial College London. Visit of Dr. Ernst was a part of the proces of setting-up collaboration between both institutions in the field of cardiology. Prior to the visit of Dr. Ernst there were several meetings in Munich and London and there was a workshop organized by FNUSA-ICRC with Prof. Dr. John Cleland and two other colleagues from Imperial College London. Both institutions also attended the Czech Heart Day in London. During her visit, Dr. Ernst had the opportunity to see the FNUSA-ICRC Cardio teams, to discuss future collaboration with FNUSA-ICRC Chair and our Grant Support Center. Dr. Ernst also gave a public lecture "Review of remote magnetic navigation: from first in man to advanced complex ablation procedures" for members of ICRC and Cardiology Department of FNUSA.

Dr. Sabina Ernst at FNUSA-ICRC
MUDr. Ing. Mgr. Petra Šedová, Ph.D. z Cerebrovaskulárního výzkumného týmu FNUSA-ICRC

15. 1. 2019

In December, Dr. Petra Šedová of our Cerebrovascular Research Team received the Martina Roesel Memorial Grant for 2018.

It is a grant to women-scientists seeking to combine quality care for their preschool children with their research career. The annual grant of 120,000 CZK is designed to help finance babysitting and other neds of working mothers. The grant is awarded by the Institute of Organic Chemistry and Biochemistry of the Academy of Sciences of the Czech Republic. "I was personally moved this idea because, as well as the grant providers, I believe that the women who care for children have tremendous potential, but they need support from the family, the environment and society as a whole," commented Petra Šedová on the grant.

Petra Sedova is a member of the Cerebrovascular Research Team led by Professor Robert Mikulík and focuses on research into new therapeutic methods for stroke.

Martina Roeselova Endowment Fund aims to support male and female scientists working in the field of natural sciences who are trying to combine competitive science with quality care for preschool children. To this end, the Fund provides selected researchers with a finnacial grant called the Martina Roeselova Memorial Prize, commemorating the prematurely deceased scientist who, during a short but excellent scientific career, managed to raise three children and actively promote the improvement of conditions for young scientist-parents. Martina Roeselova, who was not only an internationally acclaimed scientist but also a popular lecturer, trainer and colleague, died in February 2015 of cancer aged just under 50.

The award of the grant may be requested exclusively by individuals, namely Ph.D. students and postdoctoral students who take care of a preschool child while actively undertaking scientific work in the field of natural sciences at a university or non-university research centre in the Czech Republic.

Martina Roeselova was a Czech scientist working in the field of physical chemistry. In 1990 she received the title „Doctor of Natural Sciences“ at the Faculty of Mathematics and Physics of the Charles University in Prague in the field of biophysics and chemical physics. This was followed by PhD degree in the field of biophysical chemistry, chemical and macromolecular physics from the Jaroslav Hekrovsky´s Institute of Physical Chemistry at the Academy of Sciences of the Czech Republic and the Faculty of Mathematics and Physics of Charles University under the leadership of Professor Pavel Jungwirth. She successfully defended her doctoral thesis in 2003. She then spent one year as a post-doctoral researcher at the University of California Irvine and a year later joined the Institute of Organic Chemistry and Biochemistry of the Academy of Sciences (ÚOCHB), where she worked until her death. During her prolific scientific career she raised three children with the support of her husband Marek. In addition, she supported young researchers and tried to create the environment in the academic setting where one could successfully combine family life and scientific work -


Pamětní grant Martiny Roeselová pro rok 2018MUDr. Ing. Mgr. Petra Šedová, Ph.D. FNUSA-ICRC
FNUSA-ICRC - Alliance4Life in Croatian Zagreb

8. 1. 2019

The third Alliance4Life project meeting took place in Zagreb, Croatia, in early December. All focus groups participated in various lectures and workshops and, in conclusion, suggested follow-up procedures, trainings and objectives for further joint strategies and policy interventions. Alliance4Life is a bottom-up initiative of ten leading life science institutions from nine EU-13 countries that aim at closing the divide in European health research and innovation. Members of the Alliance are progressive research institutions that have the necessary strength to stimulate institutional change. Fourth project meeting will take place in June 2019.

FNUSA-ICRC Alliance4Life project meeting took place in Zagreb - Photo 1FNUSA-ICRC Alliance4Life project meeting took place in Zagreb - Photo 2
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