Apply for Martina Roeselová Endowment Fund - until September 30, 2019
2. 9. 2019
Until 30 September 2019, it is possible to apply for a grant from Martina Roeselová Endowment Fund, which is awarded for one calendar year, in the total amount of CZK 120,000. Applications are open to Ph.D. students and postdoctoral researchers caring for a preschool child or children while actively pursuing a career in natural sciences at a university or at a non-university research organization in the Czech Republic.
Last year, MD Petra Šedová received this grant.More info
New software developed by our scientists
29. 8. 2019 |
Loschmidt Laboratories announced a new version of CAVER PyMOL plugin. Bioinformatics from the FNUSA-ICRC Protein Engineering Research Team contributed to this result.
CAVER is a software tool for analysis and visualization of tunnels and channels in protein structures. Tunnels are void pathways leading from a cavity buried in a protein core to the surrounding solvent. Unlike tunnels, channels lead through the protein structure and their both endings are opened to the surrounding solvent. Studying of these pathways is highly important for drug design and molecular enzymology. It is a popular software with more than one hundred and eleven thousand downloads.
"The new version of the plugin is now compatible with the latest version of PyMOL 3.0," confirmed Jiří Damborský. “It has several enhancements for easier installation and a more user-friendly experience. The ease-of-use and user-friendliness of the new software is key to us. We develop and provide software tools to the professional community within the ELIXIR project.”
Giancarlo Forte lectured at the University of Trieste
27. 8. 2019
Giancarlo Forte, Head of the Cardiovascular System - Mechanobiology Team of FNUSA-ICRC was invited as one of the speakers at the University of Trieste, where he lectured to the students of the Summer School entitled “Nonlinear Life”.
This is the third year of this event, which was founded by the Technical University of Riga. This year's co-organizer is the University of Trieste. "Nonlinear Life is an event for twenty-five master, postgraduate or doctoral students from around the world," explained Giancarlo Forte, adding: "My lecture´s topic was Mechanically activated intracellular pathways in cell function and disease."
Students will learn about the latest trends in the fields of biomedical engineering, medical technologies or life sciences through lectures by professors from Italy, Latvia and other countries within ten days. In addition to the theoretical part, participants can learn about state-of-the-art instruments and procedures in research institutions such as Elettra Sincotrone Trieste.
The supervisory audit mandated compliance with standards and process management
23. 8. 2019 |
On July 22, 2019, external supervisory audit of quality systems according to ČSN EN ISO 9001:2016 took place in the Clinical-Pharmacological Unit (CPU) of the The International Clinical Research Center of St. Anne's University Hospital Brno and Blood bank. During the surveillance audit, no errors were found that would require withdrawal of the certificates, and in the final evaluation it was recommended to retain all the certificates for the above-mentioned quality systems. This certificate confirms compliance with standards related to process management, documentation and business organization.
"The quality system is an essential part of the operation of the CPU to ensure the highest standards when testing new drugs on patients or volunteers," added MVDr. Ing. Václav Trojan Ph.D., Head of Clinical-Pharmacological Unit. "This is another step for our unit to be able to validate the basic research findings not only of the medical cannabis we are preparing, but also of other medicines."
First EHRA accreditation in the Czech Republic awarded to the ICE team
22. 8. 2019 |
The research team of FNUSA-ICRC Interventional Cardiac Electrophysiology (ICE) was the first in the Czech Republic to be accredited as a recognized training centers by the European Heart Rhythm Association (EHRA). "This is a major achievement," said Guido Caluori, research coordinator of the ICE team, "and it is the first step towards building an EP training center in Brno with internationally recognized standards for both Czech and foreign candidates. It also serves to further put FNUSA-ICRC on the main stage of international cardiovascular research."
EHRA (European Hearth Rhythm Association) is a branch of the European Society of Cardiology (ESC). The mission of the association is improving the quality of life and reducing sudden cardiac death by limiting the impact of heart rhythm disturbances. EHRA has more than 3 500 members from across the world including physicians, arrhythmologists, young electrophysiologists, nurses and other professionals.
World experts in enzyme kinetics met in Brno
21. 8. 2019 |
Enzyme kinetics is one of the scientific disciplines, which can not do without the top equipment not only in the field of instruments, but also dynamic software. The world leader in the development of these sophisticated devices and programs is KinTek Corp. Founded by Kenneth A. Johnson.
And on his initiative and with his participation, New Enzymology Kinetics Workshops are held. The thirteenth edition took place at the beginning of the summer for the first time in Europe - in Brno. The main local organizer was prof. RNDr. Zbyněk Prokop Ph.D., member of the FNUSA-ICRC Protein Engineering research team. Thirty-two participants from all over the world gathered at the event, including academic (University of Cambridge, University of Boston, University of Münster, Francis Crick Institute) and commercial area (Roche, MyoKardia, Pentapharm, Tango Therapoeutics, etc.).
Over the four days, participants learned modern kinetic methods associated with high-resolution structural data, which provide a powerful tool for determining reaction mechanisms. Modern kinetic analysis has been described in detail using various kinetic and equilibrium methods using numerous examples of proteins and nucleic acids. The course also focused on developing the path from experimental design to data collection and analysis to gain new mechanistic perspectives. "The workshop was successful not only in terms of scientific content, it also provided a unique space for creating new international contacts," added Professor Prokop in the evaluation of the event.