Programme - ICRC - International Clinical Research Center

Tuesday, 9 September

8:00	Registration

9:00

Moderator: Pavla Hubálková

Opening Ceremony

Jan Grolich, Governor of the South Moravian Region

Markéta Vaňková, Mayor of Brno

Martin Repko, Dean, Faculty of Medicine, Masaryk University

Vlastimil Vajdák, Director, St. Anne’s University Hospital Brno

Welcome Address and Annoucement of the ICRC´s PhD Student Publication Award

Michal Masařík, Head, ICRC

Pre-clinical Research Session

9:50	Keynote Lecture Jai Prakash, Full Professor & Chair – Engineered Therapeutics, University of Twente, Netherlands \| ERC Advanced Grant \| Founder & CSO, ScarTec Therapeutics BV \| Deputy Chair, Innovation Fund Denmark
10:20	ICRC Research Teams – Session 1 Jan Frič (Cellular and Molecular Immunoregulation) – Translation research of sepsis – insights from BEATsep Robert Mikulík (STROKE)
11:10	Coffee Break
11:30	ICRC Research Teams – Session 2 Madhumalar Subramanian (Protein Engineering) – Structure-function analysis of ApoE, a key player in Alzheimer’s disease Karel Souček (Cancer Plasticity) – Cancer cell plasticity and its role in the progression of cancer diseases
12:20	Lunch Break
13:30	Keynote Lecture Yoav Shaul, Department of Biochemistry and Molecular Biology, The Institute for Medical Research Israel-Canada, The Hebrew University Medical School, Jerusalem, Israel – Tuning Ferroptosis to Target Therapy-Resistant Cancer: The GPX8–SCD Axis
14:15	ICRC Research Teams – Session 3 Lukáš Kubala (Molecular Control of Immune Response) – Adenylyl Cyclases: Isoform-Specific Architecture, Regulation, and Therapeutic Potential Pavel Šimara (Mechanobiology of Disease) – Mechanics of Life and Disease
15:00	Coffee Break
15:20	Keynote Lecture Christoph Kuppe, Emmy Noether Research Group Leader, University Clinic of the RWTH Aachen, Department of Nephrology, and Institute of Experimental Medicine and Systems Biology – Patient-level Multiomics Analysis of Human Heart Tissues Lectures of Winners of the ICRC PhD Student Publication Award
16:30	Poster Session With commentary and light refreshment; may continue during a buffet dinner
17:00	Buffet & Barbecue Dinner
21:00	End of ICRC Day 1 The program and time schedule is subject to further minor changes and clarification.

Wednesday, 10 September

9:00	Registration and Morning Coffee

Clinical Research Session

9:30	Keynote Lecture Jan Van den Bossche, Department of Molecular Cell Biology and Immunology, Amsterdam University Medical Center – Metabolic control of macrophages
10:20	ICRC Research Teams – Session 4 Martin Pešl (Interventional Cardiac Electrophysiology) – Advances in Cardiac Electrophysiology Vladimír Rotrekl (Stem Cell Disease Modeling) Milan Hluchý (Cell and Tissue Engineering) – CAR-T cells – Novel therapy for solid tumours Roman Panovský (Noninvasive Cardiac Imaging) – Shaping the Future of Cardiac Diagnostics: Highlights from the Noninvasive Cardiac Imaging (NCI) Research Group
11:30	Lunch Break
12:30	Keynote Lecture Romain Carron, Medico-Surgical Unit of Epilepsy Surgery and Functional Stereotactic Neurosurgery, Marseille University Timone Hospital, France – Functional Neurosurgery: Past, present and future. From lesion to DBS and towards non invasive temporal interference Neuromodulation
13:30	ICRC Research Teams – Session 5 Jan Cimbálnik (Biomedical Engineering) – Leveraging AI for iEEG Processing in Patients with Drug-Resistant Epilepsy Jan Škoda (Laboratory Oncology Translational Research) – Repurposing drugs for mitochondria-targeted therapies in MYC-driven pediatric tumors Ota Hlinomaz (Acute Coronary Syndromes)

14:30	Coffee Break
15:00	Keynote Lecture Nigel P. Pedersen, Vice Chair of Research and Associate Professor, Department of Neurology, University of California at Davis
15:40	ICRC Research Teams and Core Facilities – Session 6 Adam Williamson (Neuromodulation Technology) – Non-invasive Focal Deep Brain Modulation in Humans using Temporally Interfering Electric Fields Anna Bartošková (Kardiovize) – A Decade of Kardiovize: Insights from a Unique Population-Based Study in Brno Václav Trojan (Cannabis Facility)

16:30	Keynote Lecture Anna Roszkowska, Assistant Professor, Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Medical University of Gdansk – SPME-based sample preparation solutions for monitoring drugs and endogenous compounds in clinical and biomedical analysis
17:00	Wrap-Up and Official closing of the conference
18:00	ICRC Boat Party Venue: Brno Reservoir Informal networking event with refreshment (for registered only) The program and time schedule is subject to further minor changes and clarification.

General Partner of ICRC DAYS:

Partners:

Tuesday, 9 September

Opening Ceremony

Welcome Address and Annoucement of the ICRC´s PhD Student Publication Award

Pre-clinical Research Session

Keynote Lecture

ICRC Research Teams – Session 1

ICRC Research Teams – Session 2

Keynote Lecture

ICRC Research Teams – Session 3

Keynote Lecture

Lectures of Winners of the ICRC PhD Student Publication Award

Poster Session

Buffet & Barbecue Dinner

Wednesday, 10 September

Clinical Research Session

Keynote Lecture

ICRC Research Teams – Session 4

Keynote Lecture

ICRC Research Teams – Session 5

Keynote Lecture

ICRC Research Teams and Core Facilities – Session 6

Keynote Lecture

Wrap-Up and Official closing of the conference

ICRC Boat Party

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ICRC is a joint workplace of St. Anne’s University Hospital Brno and the Faculty of Medicine, Masaryk University.