Programme - ICRC - International Clinical Research Center

6th October

8:00 – 9:00	Registration
9:00 – 9:30	Opening, Welcome Address
9:30 – 10:00	Announcement of the Ph.D. Award winner, Ph.D. Award winner presentations
10:00 – 10:30	I. Keynote Speaker Alain Nogaret
10:30 – 10:50	Coffee Break
10:50 – 11:05	Martin Pešl – Electroporation Technology for the Ablation of Cardiac Arrhythmias
11:05 – 11:20	Gokula Narayanan Suryanarayanan – The effect of biomechanical stress on the RBM20-induced dilated cardiomyopathy
11:20- 11:35	Vladimír Vinarský – ECM remodelling and mechanical loading engages YAP1 dependent mechano-signalling to promote force generation and sarcomere structure development
11:35 – 11:55	Kateřina Sheardová – LIBRA: Study with yoga-mindfulness and time restricted eating in early Alzheimer patients aiming to enhance glymfatic clearance measured by proxy biomarkers
11:55 – 12:00	Microsynth – Industry Partner Presentation
12:00: – 13:30	Lunch
12:30 – 13:30	Poster Seisson
13:30 – 14:00	II. Keynote Speaker Mauro Perretti
14:00 – 14:15	Zuzana Tomášiková – Peripheral blood immune profiling reflects esophageal inflammation in paediatric patients suffering from Eosinophilic Esophagitis
14:15 – 14:30	Gabriela Blažková – IL-10 decreases fatty acid oxidation but maintains high glucose dependence in circulating monocytes
14:30 – 14:45	Ioanna Papatheodorou – IL-18 promotes epithelial remodeling alone, but induces pro-fibrotic changes during TNF-α -driven inflammation, in human iPSC-derived intestinal organoids
14:45 – 15:20	Coffee Break
15:20 – 15:40	(in Czech language) Host Lecture: Kateřina Nováková – MOÚ, BBMRI.cz – síť českých biobank
15:40 – 16:00	(in Czech language) Kristýna Baštová – ICRC Akademie
16:00 – 17:00	(in Czech language) Panelová diskuze: Budoucnost vědy začíná dnes: Příležitosti a překážky mladých vědců (nejen) v Jihomoravském kraji
from 18:00	Networking Dinner – “Tržnice Brno”, Hall with Terrace, 4th Above-Ground Floor, Zelný trh 250, 602 00 Brno-město

7th October

8:30 – 9:00	Registration
9:00 – 9:15	Geraldo Neto – Time-Dependent Efficacy of Thrombolysis Before Thrombectomy: RES-Q
9:15 – 9:30	Sandra Thalerová – In vitro vascular models for ischemic stroke research
9:30 – 9:45	Jan Česnek – From Molecular Mechanisms of Alzheimer’s Disease to Experimental Validation of ApoE-Targeted Therapeutic Candidates
9:45 – 10:00	Jan Víteček – In Vitro Models for Studying Intracranial Aneurysms
10:00 – 10:30	III. Key Note Speaker Ed Bayer
10:30 – 11:00	Coffee Break
11:00 – 11:15	Marcela Vlčnovská – Molecular Oncology
11:15 – 11:30	Veronika Knechtová – Trametinib and Axitinib Show Therapeutic Potential in Giant Cell Tumor of Bone In Vitro Models
11:30- 11:45	Adéla Kubištová – Elucidating mitochondrial synthetic lethality in MYC-driven pediatric tumors
11:45 – 12:00	Matěj Přikryl – Semi-Automated Quantification of Cancer Cell Migration in ECM-Embedded 3D Models
12:00 – 12:15	Host Lecture: Martin Falk – Surprisingly complex multifactorial mechanism of metal nanoparticle-mediated radiosensitization
12:15 – 13:00	Lunch
13:00 – 13:15	Host Lecture: Tomáš Milota – CD21low B-cell subpopulations and their role in immune system dysregulation: Common Variable Immunodeficiency as a model disease
13:15 – 13:30	Julie Zatloukalová – Effect of Vitamin D on CD4+ T cells in patients with allergic asthma
13:30 – 13:45	Lukáš Kubala – Hyaluronan as a Context-Dependent Regulator of Inflammation and Tissue Homeostasis
13:45 – 14:00	Jan Biskupič – Biological structures through elemental lens: LA-ICP-MS bioimaging in stroke research and microplastic biotoxicity
14:00 – 14:15	Zuzana Navrátil – Cognitive High-Frequency Oscillation Modulation in Human Epilepsy Networks
14:15 – 14:30	Filip Hromčík – Probiotic Nanofloss & Non‑Surgical Therapy for Dental Implant Inflammation
14:30 – 15:00	Coffee Break
15:00 – 15:15	Martin Knoz – Clinical and biotechnology research at KPECH FN USA
15:15 – 15:30	Edita Marvanová – Alterations of the Oral Microbiome in Pemphigus Vulgaris and Mucous Membrane Pemphigoid Lesion
15:30 – 15:45	Dominika Matysková – Posouzení míry osifikace chrupavek žeber pomocí ultrazvukového vyšetření: Jak vybrat vhodné donorské místo k odběru chrupavčitého štěpu?
15:45 – 16:00	Terézia Thomová – Effect of Systemic Therapies on Skin Bacteriome in Patients with Atopic Dermatitis
16:00 – 16:15	Filip Skokan – Genetická variabilita Treponema pallidum: od klinické manifestace syfilis k antimikrobiální rezistenci
16:15 – 16:30	Best Scientific Poster Award Announcement
16:30	End of ICRC DAYS 2026

Meet our keynote speakers!

Edward A. Bayer
The Wishner Chair of Bio-organic Chemistry
Weizmann Institute of Science

His research focuses on enzymes, protein interactions, and microbial systems capable of breaking down plant biomass. He is best known as one of the pioneers behind the cellulosome concept – a sophisticated enzyme complex that certain bacteria use to efficiently degrade cellulose and other components of plant cell walls.

ALAIN NOGARET
Professor of Physics
University of Bath

His research focuses on the physics of low-dimensional and nonlinear systems. In a unique way, he bridges physics and medicine, working on artificial neural networks and neuromorphic devices that mimic biological neurons, as well as the use of electronic devices for the treatment of chronic diseases. At the University of Bath, he is currently involved in the development of a digital twin of the brainstem for the treatment of cardiac disorders.

Professor Nogaret also collaborates closely with ICRC, specifically with the Interventional Cardiac Electrophysiology team and physician-scientist Martin Pešl. As part of an international consortium, they are working together on the development of an intelligent cardiac pacemaker for cardiac resynchronization therapy. The device is designed to respond to physiological signals from the patient’s body and adjust the heart rate accordingly.

Mauro Perretti
Professor of Immunopharmacology
Queen Mary University of London

His research focuses on inflammation, particularly on the emerging field of resolution pharmacology – an approach that explores how the body can actively resolve inflammation and promote the return of tissues to their normal state.

This understanding is particularly important in chronic inflammatory diseases, where the problem may not only be the inflammatory response itself, but also the body’s inability to properly switch it off. As a result, prolonged inflammation can lead to ongoing tissue damage.

Prof. Perretti’s work goes beyond basic research. He has a strong focus on translational medicine, helping to bridge the gap between scientific discoveries and their potential application in clinical practice.

Meet our keynote speakers!

contact

ICRC is a joint workplace of St. Anne’s University Hospital Brno and the Faculty of Medicine, Masaryk University.