Juan Pablo Gonzalez Rivas, MD

Research focus
The Kardiovize team is one of FNUSA-ICRC international research teams, our mission includes data acqu­isition, analysis, publication and diffusion of relevant epidemiologic and public health topics focused on cardiovascular and mental risk factors. With this knowledge intervention programs are designed, imple­mented, and evaluated in order to reduce the burden of major risk factors.

Research objectives

  • To assess the incidence and predictive value of cardiometabolic and cognitive risk factors and their determinants in the Czech population with the follow up analysis and linking with the Ministry of Health administrative datasets.
  • To design, implement, and evaluate population and individual interventions in Brno, aiming to reduce cardiovascular disease and cognitive decline risk. The intervention will be design as a translatable model to be replicated in other cities of the country.
  • To collaborate with research teams in low and middle-income countries to improve the understanding of the complex relationship among cardiometabolic, mental, and cognitive risk factors.
  • To develop and validate new technologies designed to improve the cardiometabolic health
  • To implement a Business Model to contribute with state-of-the-art evaluations and programs to the Brno population.

Main partners

  • Mayo Clinic, Rochester, MN, USA
  • Mount Sinai, NU, NY, USA
  • Charles University, Prague, Czech Republic
  • Masaryk University, Brno, Czech Republic

Offered services and expertise

  • Laboratory and diagnostic methods.
  • Individual and population-based cardiometabolic preventive programs.
  • Monitoring changes in awareness of risk factors for cardiovascular disease.
  • Tools to facilitate the implantation of lifestyle medicine.
  • Smoking cessation counseling.

Top publications 2020

  • Juan P. Gonzalez-Rivas, Jeffrey I. Mechanick, Maria M. Infante-Garcia, Jose R. Medina-Inojosa, Iuliia Pavlovska, Ota Hlinomaz, Petr Zak, Sarka Kunzova, Ramfis Nieto-Martinez, Mária Skladaná, Jan Brož, Jose Pantaleon Hernandez, Francisco Lopez-Jimenez, Gorazd B Stokin. Prevalence of Dysglycemia-Based Chronic Disease (DBCD) in a European Population: A New Paradigm to Address Diabetes Burden. The Kardiovize Study. Endocr Pract 2020 https://doi.org/10.1016/j.eprac.2020.10.003
  • Jan Sebastian Novotný, Juan Pablo Gonzalez-Rivas, Šárka Kunzová, Mária Skladaná, Anna Pospíšilová, Anna Polcrová, Jose Ramon Medina-Inojosa, Francisco Lopez-Jimenez, Yonas Endale Geda, and Gorazd Bernard Stokin Frontiers in Psychiatry. Risk Factors Underlying COVID-19 Lockdown-Induced Mental Distress. Front. Psychiatry 11:603014. doi: 10.3389/fpsyt.2020.603014

  • Andrea Maugeri, Ota Hlinomaz, Antonella Agodi, Martina Barchitta, Sarka Kunzova, Hana Bauerova 1, Ondrej Sochor 1, Jose R. Medina-Inojosa 3, Francisco Lopez-Jimenez, Manlio Vinciguerra, Gorazd Bernard Stokin, and Juan Pablo González-Rivas. Is Drinking Alcohol Really Linked to Cardiovascular Health? Evidence from the Kardiovize 2030 Project. Nutrients 2020, 12, 2848; doi:10.3390/nu12092848

  • Iuliia Pavlovska, Sarka Kunzova, Juraj Jakubik, Jana Hruskova, Maria Skladana, Irma Magaly Rivas-Serna, Jose R. Medina-Inojosa, Francisco Lopez-Jimenez, Robert Vysoky, Yonas E. Geda, Gorazd B. Stokin, Juan P. González-Rivas. Associations between high triglycerides and arterial stiffness in a population-based sample: Kardiovize Brno 2030 study. Pavlovska et al. Lipids in Health and Disease (2020) 19:170. https://doi.org/10.1186/s12944-020-01345-0

  • Nieto-Martínez R., González-Rivas J.P. (2020) Transcultural Lifestyle Medicine. In: Mechanick J., Kushner R. (eds) Creating a Lifestyle Medicine Center. Springer, Cham. https://doi.org/10.1007/978-3-030-48088-2_19

Other selected results

Kardiovize 2030 patients database – Kardiovize 2030: In the project’s first phase, was assessed the prevalence of major risk factors of cardiovascular diseases (CVD) in the target population of Brno city (400 000 inhabitants), Czech Republic, performing a randomly selected sample of 2160 volunteers aged 25-64 and following the methodology of the post-MONICA study, enrolled since January 2013 till December 2014. This survey is unique in Europe combining a detailed assessment of the traditional and some novel CVD risk factors with the evaluation of health care costs and including assessment of depression, stress, cognitive tests and resting energy expenditure. Deep frozen samples of plasma, serum or isolated DNA´s in every participant open the study to other disciplines beyond cardiology in the near future.