KARDIOVIZE

Juan Pablo Gonzalez Rivas, MD

Research focus
Kardiovize team is one of FNUSA-ICRC international research teams, our mission includes data acquisition, analysis, publication, and diffusion of relevant epidemiologic and public health topics focused on cardiovascular and mental risk factors, with this knowledge are designed, implemented, and evaluated intervention programs to reduce the burden of major risk factors and are created business opportunities that contribute with the sustainability of the institution and promotion of the population health.

Research objectives

  • To assess the cardiometabolic and cognitive risk factors and their determinants in the Czech population.
  • To implement and evaluate population and individual interventions in Brno to reduce cardiovascular diseases and cognitive decline risk, as a portable model to be replicated in others cities of the region.
  • To collaborate with researchers of low and middle-income countries to improve the understanding of the complex relationship among cardiometabolic, mental, and cognitive risk factors.
  • To develop business opportunities evaluating new technologies and providing to the Brno population access to high-quality and high-technology evaluations and programs.
  • To consolidate Kardiovize as a European leading center in cardiovascular disease prevention research.

Main partners

  • Mayo Clinic, Rochester, MN, USA
  • Mount Sinai, NU, NY, USA
  • Charles University, Prague, Czech Republic

Offered services and expertise

  • Recommended methodology of community intervention programs.
  • Population-focused prevention programs, promotion of health education.
  • Enterprise-focused prevention programs.
  • Monitoring changes in awareness of the risk factors for cardiovascular disease.
  • Laboratory and diagnostic methods.

Top publications

  • Iuliia Pavlovska, Sarka Kunzova, Juraj Jakubik, Jana Hruskova, Maria Skladana, Irma Magaly Rivas-Serna, Jose R. Medina-Inojosa, Francisco Lopez-Jimenez, Robert Vysoky, Yonas E. Geda, Gorazd B. Stokin, Juan P. González-Rivas. Associations between high triglycerides and arterial stiffness in a population-based sample: Kardiovize Brno 2030 study. Pavlovska et al. Lipids in Health and Disease (2020) 19:170.
  • SARKA KUNZOVA, ANDREA MAUGERI, JOSE MEDINA-INOJOSA, FRANCISCO LOPEZ-JIMENEZ, MANLIO VINCIGUERRA, PEDRO MARQUES-VIDAL. Determinants of Metabolic Health Across Body Mass Index Categories in Central Europe: A Comparison Between Swiss and Czech Populations. (2020) Front. Public Health 8:108.
  • ORIANA LO RE, ANDREA MAUGERI, JANA HRUSKOVA, JURAJ JAKUBIK, JAN KUCERA, JULIE BIENERTOVA-VASKU, JUDE A. OBEN, LUKAS KUBALA, ADELA DVORAKOVA, MILAN CIZ & MANLIO VINCIGUERRA. Obesity-induced nucleosome release predicts poor cardio-metabolic health. Clin Epigenet 12, 2 (2020).
  • ANDREA MAUGERI, MARTINA BARCHITTA, SARKA KUNZOVA, HANA BAUEROVA, ANTONELLA AGODI, MANLIO VINCIGUERRA. The Association of Social and Behavioral Factors with Dietary Risks in Adults: evidence from the Kardiovize Brno 2030 study. Nutrition, Metabolism and Cardiovascular Diseases Available online 24 February 2020.
  • MAUGERI, AG., HRUŠKOVÁ, J., JAKUBÍK, J., KUNZOVÁ, Š., SOCHOR, O., BARCHITTA, M., AGODI, A., BAUEROVÁ, H., MEDINA-INOJOSA, JR., VINCIGUERRA, M. Dietary antioxidant intake decreases carotid intima media thickness in women but not in men: A cross-sectional assessment in the Kardiovize study. Free Radical Biology and Medicine. 2019, 131(February), 274-281. ISSN 0891-5849. IF 5.657.

Other selected results

Kardiovize participants database: In the project’s first phase, was assessed the prevalence of major risk factors of cardiovascular diseases (CVD) in the target population of Brno city (400 000 inhabitants), Czech Republic, performing a randomly selected sample of 2160 volunteers aged 25-64 and following the methodology of the post-MONICA study, enrolled since January 2013 till December 2014. This survey is unique in Europe combining a detailed assessment of the traditional and some novel CVD risk factors with the evaluation of health care costs and including assessment of depression, stress, cognitive tests and resting energy expenditure. Deep frozen samples of plasma, serum or isolated DNA´s in every participant open the study to other disciplines beyond cardiology in the near future. The second phase of the project was focusing on the prevalence of the major CVD risk factors in the elderly participants. Participants were enrolling based on the relationship (parents or the foster parents of the participants) with the baseline cohort from the first phase. The third phase is focused on the cardiovascular changes in the baseline cohort of the KV Brno 2030 study.