The Industrial Property Office entered three new utility models in the utility model database, which were created in the International Clinical Research Center of St. Anne’s University Hospital Brno (FNUSA-ICRC). Two of them were developed by researchers of the Interventional cardiac electrophysiology research team led by MUDr. Zdeněk Stárek, Ph.D., one of them is the team Inflammation led by Mgr. Lukáš Kubala, PhD. “This is the result of collaboration between research teams, technology transfer and patent attorneys,” emphasized Roman Polák from FNUSA-ICRC Technology Transfer Department. “These are the first three early birds, we are currently expecting more registered utility models, and working with researchers to protect patent solutions. And of course we will also actively help with their commercialization.”
The first utility model is called the “Kit for Determining the Specific Influence of Adenylate Cyclase (AC) Isoforms”. There are currently a large number of available drugs, especially antihistamines or antiasthmatics, which modulate AC activity through receptors. However, more than 750 subtypes of these receptors are described and their specific modulation is very problematic. To date, only ten different AC isoforms have been identified that can be regulated differently, and research into new modulators suggests that AC can become a direct therapeutic target for next-generation drugs. To date, however, there was no commercially available technology to test for selective modulation of AC activity sensitive to the non-selective activator forskolin. These disadvantages and shortcomings are eliminated by the kit of which technical solution is the subject of the utility model.
Two other utility models entitled “High Voltage AC Source for Electroporation Purposes” and “Electroporation Generator for Ablation of Cardiac Tissues”, which was filed together with the Brno University of Technology, deal with the issue of catheter ablation of cardiac arrhythmias. Utility models are related to electroporation, this energy source is in many ways better than existing technology in terms of safety and sustained normal heart rhythm.
Two above mentioned utility models were developed in the TA ČR Gamma program: Support for verification and commercialization of research and development results at FNUSA in Brno, project number: TG02010048.