TOP 1
1. BELLENGUEZ, C., F. KUCUKALI, I. E. JANSEN, L. KLEINEIDAM, et al. New insights into the genetic etiology of Alzheimer’s disease and related dementias. Nature Genetics, Apr 2022, 54(4), 412-+.
2. RAFFAELE, M. AND M. VINCIGUERRA The costs and benefits of senotherapeutics for human health. Lancet Global Health, Jan 2022, 3(1), E67-E77.

TOP 5
3. BHANGU, S. K., S. FERNANDES, G. L. BERETTA, S. TINELLI, et al. Transforming the Chemical Structure and Bio-Nano Activity of Doxorubicin by Ultrasound for Selective Killing of Cancer Cells. Advanced Materials, Apr 2022, 34(13), 16.
4. OWOLABI, M. O., A. G. THRIFT, A. MAHAL, M. ISHIDA, et al. Primary stroke prevention worldwide: translating evidence into action. Lancet Public Health, Jan 2022, 7(1), E74-E85.
5. VARADI, M., S. ANYANGO, D. ARMSTRONG, J. BERRISFORD, et al. PDBe-KB: collaboratively defining the biological context of structural data. Nucleic Acids Research, Jan 2022, 50(D1), D534-D542.

TOP 10
6. BOUCHALOVA, P., L. SOMMEROVA, D. POTESIL, A. MARTISOVA, et al. Characterization of the AGR2 Interactome Uncovers New Players of Protein Disulfide Isomerase Network in Cancer Cells. Molecular & Cellular Proteomics, Feb 2022, 21(2), 19.
7. COKU, J., D. M. BOOTH, J. SKODA, M. C. PEDROTTY, et al. Reduced ER-mitochondria connectivity promotes neuroblastoma multidrug resistance. Embo Journal, Apr 2022, 41(8), 20.
8. RAFFAELE, M., K. KOVACOVICOVA, T. BIAGINI, O. LO RE, et al. Nociceptin/orphanin FQ opioid receptor (NOP) selective ligand MCOPPB links anxiolytic and senolytic effects. Geroscience, Feb 2022, 44(1), 463-483.
9. TOUL, M., D. NIKITIN, M. MAREK, J. DAMBORSKY, et al. Extended Mechanism of the Plasminogen Activator Staphylokinase Revealed by Global Kinetic Analysis: 1000-fold Higher Catalytic Activity than That of Clinically Used Alteplase. Acs Catalysis, Apr 2022, 12(7), 3807-3814.
10. WEI, R., G. VON HAUGWITZ, L. PFAFF, J. MICAN, et al. Mechanism-Based Design of Efficient PET Hydrolases. Acs Catalysis, Mar 2022, 12(6), 3382-3396.
11. ZIEBA, J., K. N. FORLENZA, K. HEARD, J. H. MARTIN, et al. Intervertebral disc degeneration is rescued
by TGF beta/BMP signaling modulation in an ex vivo filamin B mouse model. Bone Research, Apr 2022, 10(1), 12.

Q1
12. ABRAHAM, S. P., A. NITA, P. KREJCI AND M. BOSAKOVA Cilia kinases in skeletal development and homeostasis. Developmental Dynamics, Apr 2022, 251(4), 577-608.
13. AMLEROVA, J., J. LACZO, Z. NEDELSKA, M. LACZO, et al. Emotional prosody recognition is impaired in Alzheimer’s disease. Alzheimers Research & Therapy, Apr 2022, 14(1), 8.
14. AMODIO, A., M. CASSANI, L. MUMMOLO, C. CORTEZ-JUGO, et al. Nanoscale probing and imaging of HIV-1 RNA in cells with a chimeric LNA-DNA sensor. Nanoscale, Feb 2022, 14(8), 3049-3061.
15. CIMBALNIK, J., J. DOLEZAL, C. TOPCU, M. LECH, et al. Intracranial electrophysiological recordings from the human brain during memory tasks with pupillometry. Scientific Data, Jan 2022, 9(1), 10.
16. CURYLOVA, L., H. RAMOS, L. SARAIVA AND J. SKODA Noncanonical roles of p53 in cancer stemness and their implications in sarcomas. Cancer Letters, Jan 2022, 525, 131-145.
17. DE ZUANI, M., C. DAL SECCO, S. TONON, A. ARZESE, et al. LPS Guides Distinct Patterns of Training and Tolerance in Mast Cells. Frontiers in Immunology, Feb 2022a, 13, 14.
18. DE ZUANI, M. AND J. FRIC Train the Trainer: Hematopoietic Stem Cell Control of Trained Immunity. Frontiers in Immunology, Jan 2022, 13, 9.
19. DURAN, I., J. ZIEBA, F. CSUKASI, J. H. MARTIN, et al. 4-PBA Treatment Improves Bone Phenotypes in the Aga2 Mouse Model of Osteogenesis Imperfecta. Journal of Bone and Mineral Research, Apr 2022, 37(4), 675-686.
20. FOROUGHI, M., J. M. R. INOJOSA, F. LOPEZ-JIMENEZ, F. SAEIDIFARD, et al. Association of Bipolar Disorder With Major Adverse Cardiovascular Events: A Population-Based Historical Cohort Study. Psychosomatic Medicine, Jan 2022, 84(1), 97-103.
21. GIALLONGO, S., D. REHAKOVA, T. BIAGINI, O. LO RE, et al. Histone Variant macroH2A1.1 Enhances Nonhomologous End Joining-dependent DNA Double-strand-break Repair and Reprogramming Efficiency of Human iPSCs. Stem Cells, Mar 2022, 40(1), 35-48.
22. HELAN, M., J. MALASKA, J. TOMANDL, J. JARKOVSKY, et al. Kinetics of Biomarkers of Oxidative Stress in Septic Shock: A Pilot Study. Antioxidants, Apr 2022, 11(4), 12.
23. JANSSEN, P. M., K. VAN OVERHAGEN, J. VINKLAREK, B. ROOZENBEEK, et al. Between-Center Variation in Outcome After Endovascular Treatment of Acute Stroke: Analysis of Two Nationwide Registries. Circulation-Cardiovascular Quality and Outcomes, Mar 2022, 15(3), 10.
24. KLIMOVIC, S., M. SCUREK, M. PESL, D. BECKEROVA, et al. Aminophylline Induces Two Types of Arrhythmic Events in Human Pluripotent Stem Cell-Derived Cardiomyocytes. Frontiers in Pharmacology, Jan 2022, 12, 12.
25. KREMSEROVA, S., A. KOCURKOVA, M. CHORVATOVA, A. KLINKE, et al. Myeloperoxidase Deficiency Alters the Process of the Regulated Cell Death of Polymorphonuclear Neutrophils. Frontiers in Immunology, Feb 2022, 13, 16.
26. LEE, Y. J., E. GONZALES AND R. ANDEL Multifaceted Demands of Work and Cognitive Functioning: Findings From the Health and Retirement Study. Journals of Gerontology Series B-Psychological Sciences and Social Sciences, Feb 2022, 77(2), 351-361.
27. MACSEK, P., J. SKODA, M. KRCHNIAKOVA, J. NERADIL, et al. Iron-Chelation Treatment by Novel Thiosemicarbazone Targets Major Signaling Pathways in Neuroblastoma. International Journal of Molecular Sciences, Jan 2022, 23(1), 18.
28. MANDAL, G., L. MORAN, L. PECINKA, P. VANHARA, et al. Matrix enrichment by black phosphorus improves ionization and reproducibility of mass spectrometry of intact cells, peptides, and amino acids. Scientific Reports, Jan 2022, 12(1), 10.
29. MIVALT, F., V. KREMEN, V. SLADKY, I. BALZEKAS, et al. Electrical brain stimulation and continuous behavioral state tracking in ambulatory humans. Journal of Neural Engineering, Feb 2022, 19(1), 13.
30. OPATRIL, L., R. PANOVSKY, M. MOJICA-PISCIOTTI, J. MACHAL, et al. Stress pulmonary circulation parameters assessed by a cardiovascular magnetic resonance in patients after a heart transplant. Scientific Reports, Apr 2022, 12(1), 10.
31. RADZIWON, A., S. K. BHANGU, S. FERNANDES, C. CORTEZ-JUGO, et al. Triggering the nanophase separation of albumin through multivalent binding to glycogen for drug delivery in 2D and 3D multicellular constructs. Nanoscale, Mar 2022, 14(9), 3452-3466.
32. SAFARIKOVA, E., J. EHLICH, S. STRITESKI, M. VALA, et al. Conductive Polymer PEDOT:PSS-Based Platform for Embryonic Stem-Cell Differentiation. International Journal of Molecular Sciences, Feb 2022, 23(3), 16.
33. SALA, M., V. KINCL, M. KAMINEK, J. VASINA, et al. Assessment of left ventricular volumes and ejection fraction using ultra-low-dose thallium-201 SPECT on a CZT camera: a comparison with magnetic resonance imaging. Journal of Nuclear Cardiology, Feb 2022, 29(1), 181-187.
34. TONON, F., M. CEMAZAR, U. KAMENSEK, C. ZENNARO, et al. 5-Azacytidine Downregulates the Proliferation and Migration of Hepatocellular Carcinoma Cells In Vitro and In Vivo by Targeting miR139-5p/ROCK2 Pathway. Cancers, Apr 2022, 14(7), 34.
35. VESELA, B., M. KILLINGER, K. RIHOVA, P. BENES, et al. Caspase-8 Deficient Osteoblastic Cells Display Alterations in Non-Apoptotic Pathways. Frontiers in Cell and Developmental Biology, Mar 2022, 10, 11.
36. ZAMOCKY, M., M. MUSIL, M. DANCHENKO, P. FERIANC, et al. Deep Insights into the Specific Evolution of Fungal Hybrid B Heme Peroxidases. Biology-Basel, Mar 2022, 11(3), 18.

Q2
37. BARAK, M., V. FEDOROVA, V. POSPISILOVA, J. RASKA, et al. Human iPSC-Derived Neural Models for Studying Alzheimer’s Disease: from Neural Stem Cells to Cerebral Organoids. Stem Cell Reviews and Reports, Feb 2022, 18(2), 792-820.
38. BAUMANN, I., H. S. EYJOLFSDOTTIR, J. FRITZELL, C. LENNARTSSON, et al. Do cognitively stimulating activities affect the association between retirement timing and cognitive functioning in old age? Ageing & Society, Feb 2022, 42(2), 306-330.
39. GOBOM, J., L. PARNETTI, P. ROSA-NETO, M. VYHNALEK, et al. Validation of the LUMIPULSE automated immunoassay for the measurement of core AD biomarkers in cerebrospinal fluid. Clinical Chemistry and Laboratory Medicine, Jan 2022, 60(2), 207-219.
40. JADCZYK, T., J. WOLF, M. PESL, F. SOUCEK, et al. Reduced Radiation Exposure Protocol during Computer Tomography of the Left Atrium Prior to Catheter Ablation in Patients with Atrial Fibrillation. Diagnostics, Mar 2022, 12(3), 12.
41. JESTER, D. J., M. VYHNALEK, R. ANDEL, H. MARKOVA, et al. Progression from Subjective Cognitive Decline to Mild Cognitive Impairment or Dementia: The Role of Baseline Cognitive Performance. Journal of Alzheimers Disease, 2022, 86(4), 1763-1774.
42. KABANOV, D., S. KLIMOVIC, V. ROTREKL, M. PESL, et al. Atomic force spectroscopy is a promising tool to study contractile properties of cardiac cells. Micron, Apr 2022, 155, 8.
43. KINCL, V., R. PANOVSKY, T. KEPAK, V. BAJCIOVA, et al. Assessment of late cardiotoxic effects in patients treated for cancer in childhood. Cancer Medicine, Apr 2022, 11(8), 1763-1768.
44. KOCURKOVA, A., K. NESPOROVA, M. SANDANUSOVA, M. KERBEROVA, et al. EndogenouslyProduced Hyaluronan and Its Potential to Regulate the Development of Peritoneal Adhesions. Biomolecules, Jan 2022, 12(1), 17.
45. LERCH, O., M. LACZO, M. VYHNALEK, Z. NEDELSKA, et al. APOE epsilon 4 Allele Moderates the Association Between Basal Forebrain Nuclei Volumes and Allocentric Navigation in Older Adults Without Dementia. Journal of Alzheimers Disease, 2022, 86(1), 155-171.
46. MASURI, S., P. VANHARA, M. G. CABIDDU, L. MORAN, et al. Copper(II) Phenanthroline-Based Complexes as Potential AntiCancer Drugs: A Walkthrough on the Mechanisms of Action. Molecules, Jan 2022, 27(1), 26.
47. PAVLIK, V., V. MACHALOVA, M. CEPA, R. SINOVA, et al. Retinoic Acid Grafted to Hyaluronic Acid Activates Retinoid Gene Expression and Removes Cholesterol from Cellular Membranes. Biomolecules, Feb 2022, 12(2), 14.
48. RIHOVA, K., M. DUCKA, I. S. ZAMBO, L. VYMETALOVA, et al. Transcription factor c-Myb: novel prognostic factor in osteosarcoma. Clinical & Experimental Metastasis, Apr 2022, 39(2), 375-390.
49. SCUREK, M., E. POKOJOVA, M. DOUBKOVA AND K. BRAT Allergic bronchopulmonary candidiasis: A review of the literature and a case report. Bmc Pulmonary Medicine, Apr 2022, 22(1), 6.
50. SOUKUP, L., P. JURAK, J. HALAMEK, I. VISCOR, et al. Arterial Aging Best Reflected in Pulse Wave Velocity Measured from Neck to Lower Limbs: A Whole-Body Multichannel Bioimpedance Study. Sensors, Mar 2022, 22(5), 12.
51. VAZQUEZ-GOMEZ, G., M. KARASOVA, Z. TYLICHOVA, M. KABATKOVA, et al. Aryl Hydrocarbon Receptor (AhR) Limits the Inflammatory Responses in Human Lung Adenocarcinoma A549 Cells via Interference with NF-kappa B Signaling. Cells, Feb 2022, 11(4), 19.
52. WOLFF, J. E., S. W. VAN GOOL, T. KUTLUK, B. DIEZ, et al. Final results of the Choroid Plexus Tumor study CPT-SIOP-2000. Journal of Neuro-Oncology, Feb 2022, 156(3), 599-613.

Q3
53. DE ZUANI, M., P. LAZNICKOVA, V. TOMASKOVA, M. DVONCOVA, et al. High CD4-to-CD8 ratio identifies an at-risk population susceptible to lethal COVID-19. Scandinavian Journal of Immunology, Mar 2022b, 95(3), 11.
54. DOSBABA, F., M. HARTMAN, L. BATALIK, K. BRAT, et al. Test of incremental respiratory endurance as home-based, stand-alone therapy in chronic obstructive pulmonary disease: A case report. World Journal of Clinical Cases, Jan 2022, 10(1), 353-360.
55. FRIEND, E. J., P. LEINVEBER, M. ORBAN, J. HOCHHOLD, et al. Obstructive sleep apnea in patients with acute aortic dissection. Clinical Cardiology, Apr 2022, 45(4), 386-390.
56. PIETERSZ, K. L., S. POUW, J. KLIMA, Z. ELLEDEROVA, et al. Transduction profiles in minipig following MRI guided delivery of AAV-5 into thalamic and corona radiata areas. Journal of Neuroscience Methods, Jan 2022, 365, 9.
57. QUAST, T., R. ANDEL, S. GREGORY AND E. A. STORCH Years of life lost associated with COVID-19 deaths in the USA during the first year of the pandemic. Journal of Public Health, Mar 2022, 44(1), E20-E25.

Q4
58. BOSCH, J., L. A. PEARCE, M. SHARMA, R. MIKULIK, et al. Functional Abilities of an International PostStroke Population: Standard Assessment of Global Everyday Activities (SAGEA) Scale. Journal of Stroke & Cerebrovascular Diseases, Apr 2022, 31(4), 8.
59. IVANA, T., P. ROBERT, S. PAVEL, T. LENKA, et al. Cytomegalovirus and other herpesviruses after hematopoietic cell and solid organ transplantation: From antiviral drugs to virus-specific T cells. Transplant Immunology, Apr 2022, 71, 13.

N/A
60. DOLEZALOVA, K., F. LEHAR, J. JEZ, M. PESL, et al. Efficacy and safety of endocardial radiofrequency catheter ablation of interventricular septal hypertrophy in the treatment of hypertrophic obstructive cardiomyopathy. Cor Et Vasa, Feb-Mar 2022, 64(1), 53-59.